115 In a rat model of short bowel syndrome, transplantation of small intestinal organoids into the colon partially restores intestinal function and improves survival—a proof of principle that organoid transplantation might have therapeutic benefit.
https://www.nature.com/articles/s41586-021-03247-2
114 Lymphoangiocrine signals promote cardiac growth and repair.
https://www.nature.com/articles/s41586-020-2998-x
113 Mammalian-specific ectodermal enhancers control the expression of Hoxc genes in developing nails and hair follicles.
https://www.pnas.org/content/117/48/30509
112 Macrophage-derived glutamine boosts satellite cells and muscle regeneration.
https://www.nature.com/articles/s41586-020-2857-9
111 NF-κB activation persists into the remodeling phase of tendon healing and promotes myofibroblast survival.
https://stke.sciencemag.org/content/13/658/eabb7209
110 Mohawk is a transcription factor that promotes meniscus cell phenotype and tissue repair and reduces osteoarthritis severity.
https://stm.sciencemag.org/content/12/567/eaan7967
109 Tissue engineered autologous cartilage-bone grafts for temporomandibular joint regeneration.
https://stm.sciencemag.org/content/12/565/eabb6683
108 Inducible expression of a transcription factor causes spinal cord stem cells to generate oligodendrocytes that can promote remyelination.
https://science.sciencemag.org/content/370/6512/eabb8795
107 Agrin induces long-term osteochondral regeneration by supporting repair morphogenesis.
https://stm.sciencemag.org/content/12/559/eaax9086
106 Transforming the spleen into a liver-like organ in vivo.
https://advances.sciencemag.org/content/6/24/eaaz9974
105 A planarian fission protocol shows that the number of progeny and the frequency of fission initiation correlate with parent size, and TGFβ and Wnt signalling components are identified as regulators of fission behaviour.
https://www.nature.com/articles/s41586-019-1478-7
104 Biofabrication of contractile ventricles, heart valves, vascular networks, and organ-scale scaffolds using collagen is explored.
https://science.sciencemag.org/content/365/6452/482
103 Identification of a regeneration-organizing cell in the Xenopus tail.
https://science.sciencemag.org/content/364/6441/653?intcmp=trendmd-sci
102 Regenerative and durable small-diameter graft as an arterial conduit.
https://www.pnas.org/content/116/26/12710
101 Recapitulating bone development through engineered mesenchymal condensations and mechanical cues for tissue regeneration.
https://stm.sciencemag.org/content/11/495/eaav7756
100 Liquid biopsy of circulating exosomes can be used to monitor recovery of ischemic myocardium after transplanting cardiac progenitor cells.
https://stm.sciencemag.org/content/11/493/eaau1168
99 Identification of a regeneration-organizing cell in the Xenopus tail.
https://science.sciencemag.org/content/364/6441/653
98 Single-cell-based imaging and sequencing approaches are used to characterize organoid development and the intestinal regeneration process, which is driven by transient activation of YAP1.
https://www.nature.com/articles/s41586-019-1146-y
97 A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix.
https://stm.sciencemag.org/content/11/489/eaar4953
96 Bioengineered human acellular vessels repopulate with host cells and evolve into self-sustaining living blood vessels in hemodialysis patients.
http://stm.sciencemag.org/content/11/485/eaau6934
|
