Cardiology

Articles:

304 CAR T cells produced in vivo to treat cardiac injury.
https://www.science.org/doi/10.1126/science.abm0594

303 Exome sequencing identifies a genetic variant with protective effects in cardiovascular disease.
https://www.science.org/doi/10.1126/science.abe0348

302 Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice.
https://www.science.org/doi/10.1126/science.abg5159

301 APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans.
https://www.nature.com/articles/s41586-021-03818-3

300 Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects.
https://www.pnas.org/content/118/20/e2024215118

299 SARS-CoV-2 infection of human iPSC–derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19.
https://stm.sciencemag.org/content/13/590/eabf7872

298 Blocking endothelial lipase with monoclonal antibody MEDI5884 durably increases high density lipoprotein in nonhuman primates and in a phase 1 trial.
https://stm.sciencemag.org/content/13/590/eabb0602

297 Implantation of a perfusable device into the epicardium enables delivery of therapeutic agents and infiltration of reparative cells into the heart, amplifying the therapeutic effects of FGF-23 in a rat model of myocardial infarction.
https://www.nature.com/articles/s41591-021-01279-9

296 A transcription factor coordinates cardiomyocyte dedifferentiation and proliferation in adult hearts.
https://science.sciencemag.org/content/372/6538/201

295 The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis.
https://www.nature.com/articles/s41586-021-03341-5

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