59 Discovery of T Cell Antigens by High-Throughput Screening of Synthetic Minigene Libraries.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0029949
58 Bubblegrams Reveal the Inner Body of Bacteriophage ϕKZ.
http://www.sciencemag.org/content/335/6065/182.abstract
57 Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin.
http://www.pnas.org/content/109/2/413.abstract
56 Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells.
http://www.pnas.org/content/109/2/419.abstract
55 Optical recording of action potentials in mammalian neurons using a microbial rhodopsin.
http://www.nature.com/nmeth/journal/v9/n1/abs/nmeth.1782.html
54 Global profiling of dynamic protein palmitoylation.
http://www.nature.com/nmeth/journal/v9/n1/abs/nmeth.1769.html
53 Decoding cell lineage from acquired mutations using arbitrary deep sequencing.
http://www.nature.com/nmeth/journal/v9/n1/abs/nmeth.1781.html
52 Unique molecular identifiers (UMIs) associate distinct sequences with every DNA or RNA molecule and can be counted after amplification to quantify molecules in the original sample. Using UMIs, the authors obtain a digital karyotype of an individual with Down's syndrome and quantify mRNA in Drosophila melanogaster cells.
http://www.nature.com/nmeth/journal/v9/n1/abs/nmeth.1778.html
51 Conjugation of triplet-state quenchers to the small organic cyanine fluorophore, Cy5, increases photostability without affecting its spectral characteristics. This allows longer fluorescence imaging with a concomitant reduction in blinking both in vitro and in living cells.
http://www.nature.com/nmeth/journal/v9/n1/abs/nmeth.1774.html
50 Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery.
http://www.nature.com/nmat/journal/v11/n1/abs/nmat3187.html
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