451 Comprehensive molecular characterization of gastric adenocarcinoma.
http://www.nature.com/nature/journal/v513/n7517/full/nature13480.html
450 Asymmetric triplex metallohelices with high and selective activity against cancer cells.
http://www.nature.com/nchem/journal/v6/n9/abs/nchem.2024.html
449 The role of PI3K/AKT-related PIP5K1α and the discovery of its selective inhibitor for treatment of advanced prostate cancer.
http://www.pnas.org/content/111/35/E3689.abstract
448 The translation of many messenger RNAs that encode important oncogenes and transcription factors depends on the eIF4A RNA helicase to resolve G-quadruplex structures, implying eIF4A inhibition as an effective cancer therapy.
http://www.nature.com/nature/journal/v513/n7516/full/nature13485.html
447 Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia.
http://www.nature.com/nature/journal/v513/n7516/full/nature13528.html
446 Predicting Cancer-Specific Vulnerability via Data-Driven Detection of Synthetic Lethality.
http://www.cell.com/cell/abstract/S0092-8674(14)00977-5
445 Small RNA combination therapy for lung cancer.
http://www.pnas.org/content/111/34/E3553.abstract
444 A vaccine targeting mutant IDH1 induces antitumour immunity.
http://www.nature.com/nature/journal/v512/n7514/full/nature13387.html
443 Clonal evolution in breast cancer revealed by single nucleus genome sequencing.
http://www.nature.com/nature/journal/v512/n7513/full/nature13600.html
442 miRNA-128 Suppresses Prostate Cancer by Inhibiting BMI-1 to Inhibit Tumor-Initiating Cells.
http://cancerres.aacrjournals.org/content/74/15/4183.abstract
441 DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer Therapy.
http://pubs.acs.org/doi/abs/10.1021/nn502058j
440 DEPDC1/LET-99 participates in an evolutionarily conserved pathway for anti-tubulin drug-induced apoptosis.
http://www.nature.com/ncb/journal/v16/n8/abs/ncb3010.html
439 Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells.
http://www.nature.com/ncb/journal/v16/n8/abs/ncb2994.html
438 Tumor genomes are peppered with mobile repeat sequences that carry along adjacent DNA when they insert into new genomic sites.
http://www.sciencemag.org/content/345/6196/1251343.abstract
437 Platelets guide the formation of early metastatic niches.
http://www.pnas.org/content/111/30/E3053.abstract
436 Immunosignature system for diagnosis of cancer.
http://www.pnas.org/content/111/30/E3072.abstract
435 Targeting transcription regulation in cancer with a covalent CDK7 inhibitor.
http://www.nature.com/nature/journal/v511/n7511/full/nature13393.html
434 Comprehensive molecular profiling of lung adenocarcinoma.
http://www.nature.com/nature/journal/v511/n7511/full/nature13385.html
433 Inducing changes in the levels of the MYC oncoprotein is shown to activate and repress specific sets of target genes that are characteristic of tumour cells, providing an insight into the mechanism by which MYC can stimulate tumorigenesis in contrast to its physiological role.
http://www.nature.com/nature/journal/v511/n7510/full/nature13473.html
432 Pulsed, ultrahigh dose-rate irradiation is safer than standard radiotherapy for the treatment of lung cancer and selectively spares normal tissue.
http://stm.sciencemag.org/content/6/245/245ra93.abstract
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