1245 ARCoV is an LNP-encapsulated mRNA vaccine platform that is highly immunogenic and safe in mice and non-human primates, conferring protection against challenge with a SARS-CoV-2 mouse-adapted strain.
https://www.cell.com/cell/fulltext/S0092-8674(20)30932-6
1244 The bifunctional compound D18 improves checkpoint blockade efficacy by increasing KDM5A and PD-L1 abundance and inducing TLR7/8 activation.
https://stm.sciencemag.org/content/12/560/eaax2282
1243 Activation of TRPA1 nociceptor promotes systemic adult mammalian skin regeneration.
https://immunology.sciencemag.org/content/5/50/eaba5683
1242 Lymph protects metastasizing melanoma cells from ferroptosis.
https://www.nature.com/articles/s41586-020-2623-z
1241 An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma.
https://www.nature.com/articles/s41586-020-2537-9
1240 cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity.
https://www.nature.com/articles/s41586-020-2611-3
1239 Potently neutralizing and protective human antibodies against SARS-CoV-2.
https://www.nature.com/articles/s41586-020-2548-6
1238 A safeguard mechanism protects cells against aberrant immune responses toward their own genomic DNA.
https://science.sciencemag.org/content/369/6505/823
1237 Structures of human CD20 in complexes with therapeutic antibodies reveal molecular mechanisms underlying cancer immunotherapies.
https://science.sciencemag.org/content/369/6505/793
1236 Erythrocyte-driven immunization via biomimicry of their natural antigen-presenting function.
https://www.pnas.org/content/117/30/17727
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