1055 Glycosylation may hold the key for designing effective HIV nanoparticle–based vaccines.
http://science.sciencemag.org/content/363/6427/649
1054 Choline acetyltransferase–expressing T cells are required to control chronic viral infection.
http://science.sciencemag.org/content/363/6427/639
1053 Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease.
https://www.nature.com/articles/s41586-018-0849-9
1052 In the mouse intestine, pyruvate and lactate produced from bacterial metabolites enhance immune responses through inducing dendrite protrusion, mediated by GPR31, of small intestinal mononuclear cells that express CX3CR1.
https://www.nature.com/articles/s41586-019-0884-1
1051 Dynamically reprogrammed neutrophils serve as critical initiators for the pathogenesis and treatment of atherosclerosis.
http://advances.sciencemag.org/content/5/2/eaav2309
1050 A sleep-inducing gene, nemuri, links sleep and immune function in Drosophila.
http://science.sciencemag.org/content/363/6426/509
1049 Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope.
https://www.pnas.org/content/116/5/1591
1048 A consortium of 11 bacterial strains from the healthy human gut microbiota can strongly induce interferon-γ-producing CD8 T cells in the intestine, and enhance both resistance to bacterial infection and the therapeutic efficacy of immune checkpoint inhibitors.
https://www.nature.com/articles/s41586-019-0878-z
1047 A vaccine platform has been developed from a polymeric glyco-adjuvant conjugated to an antigen, and is now shown to target dendritic cells via mannose-binding receptors and generate potent cellular and humoral immune response against malaria.
https://www.nature.com/articles/s41563-018-0256-5
1046 A defined commensal consortium elicits CD8 T cells and anti-cancer immunity.
https://www.nature.com/articles/s41586-019-0878-z
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