1035 FGL1 is identified as a major ligand for the inhibitory receptor LAG-3, and its blockade can potentiate anti-tumor T cell responses.
https://www.cell.com/cell/fulltext/S0092-8674(18)31502-2
1034 In chronic inflammatory lung disease, neutrophil-derived pathogenic exosomes bypass the pulmonary antiprotease barrier to promote extracellular matrix destruction.
https://www.cell.com/cell/fulltext/S0092-8674(18)31585-X
1033 Actively personalized vaccination trial for newly diagnosed glioblastoma.
https://www.nature.com/articles/s41586-018-0810-y
1032 Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery.
https://www.nature.com/articles/s41586-018-0824-5
1031 Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.
https://www.nature.com/articles/s41586-018-0792-9
1030 Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10.
https://www.sciencedirect.com/science/article/pii/S0092867418315605?via%3Dihub
1029 De novo design of potent and selective mimics of IL-2 and IL-15.
https://www.nature.com/articles/s41586-018-0830-7
1028 Skin-resident T cells co-opt tissue residency and cell-intrinsic flexibility to promote local immunity in response to injury.
http://science.sciencemag.org/content/363/6422/eaat6280
1027 Combination cancer immunotherapy targeting PD-1 and GITR can rescue CD8+ T cell dysfunction and maintain memory phenotype.
http://immunology.sciencemag.org/content/3/29/eaat7061
1026 T cell receptor–triggered nuclear actin network formation drives CD4+ T cell effector functions.
http://immunology.sciencemag.org/content/4/31/eaav1987
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