503 The analysis of multiple SIV vaccine regimens in macaques leads to the identification of a key two-amino-acid signature that confers resistance to neutralizing antibodies; a similar mechanism of immune escape is shown to operate in HIV and may explain the limited efficacy seen in HIV vaccine trials.
http://www.nature.com/nature/journal/v505/n7484/full/nature12893.html
502 Gut Microbiota of the Tick Vector Ixodes scapularis Modulate Colonization of the Lyme Disease Spirochete.
http://www.cell.com/cell-host-microbe/abstract/S1931-3128(13)00434-4
501 Chlamydia trachomatis-Induced Alterations in the Host Cell Proteome Are Required for Intracellular Growth.
http://www.cell.com/cell-host-microbe/abstract/S1931-3128(13)00442-3
500 Bacterial Lipopolysaccharide Binding Enhances Virion Stability and Promotes Environmental Fitness of an Enteric Virus.
http://www.cell.com/cell-host-microbe/abstract/S1931-3128(13)00437-X
499 An Extracellular Bacterial Pathogen Modulates Host Metabolism to Regulate Its Own Sensing and Proliferation.
http://www.cell.com/abstract/S0092-8674(13)01539-0
498 Sphingolipids from a Symbiotic Microbe Regulate Homeostasis of Host Intestinal Natural Killer T Cells.
http://www.cell.com/abstract/S0092-8674(13)01528-6
497 The Bacterial Cytoplasm Has Glass-like Properties and Is Fluidized by Metabolic Activity.
http://www.cell.com/abstract/S0092-8674(13)01479-7
496 Icosahedral bacteriophage ΦX174 forms a tail for DNA transport during infection.
http://www.nature.com/nature/journal/v505/n7483/full/nature12816.html
495 The airway mucin Muc5b (but not Muc5ac) is required for mucociliary clearance, defence against bacterial infection in the airways and middle ear, and maintenance of immune homeostasis in the lungs; Muc5b deficiency causes accumulation of apoptotic macrophages, impairment of phagocytosis and reduced production of interleukin-23, leading to infection and inflammation.
http://www.nature.com/nature/journal/v505/n7483/full/nature12807.html
494 Upon internalization, intracellular Salmonella choose between replication or a form of quiescence known as persistence.
http://www.sciencemag.org/content/343/6167/204.abstract
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