473 Real-time reliable determination of binding kinetics of DNA hybridization using a multi-channel graphene biosensor.
http://www.nature.com/articles/ncomms14902
472 An atlas of human long non-coding RNAs with accurate 5′ ends.
http://www.nature.com/nature/journal/v543/n7644/full/nature21374.html
471 Adipose-derived circulating miRNAs regulate gene expression in other tissues.
http://www.nature.com/nature/journal/v542/n7642/full/nature21365.html
470 Genome-wide mapping of autonomous promoter activity in human cells.
http://www.nature.com/nbt/journal/v35/n2/abs/nbt.3754.html
469 Imaging proteins at the single-molecule level.
http://www.pnas.org/content/114/7/1474
468 New CRISPR–Cas systems from uncultivated microbes.
http://www.nature.com/nature/journal/v542/n7640/full/nature21059.html
467 The application of genome-wide CRISPR–Cas9 screening coupled with a fluorescent reporter to interrogate the microRNA pathway reveals that continual transient phosphorylation of Argonaute 2 is required to maintain the global efficiency of microRNA-mediated repression.
http://www.nature.com/nature/journal/v542/n7640/full/nature21025.html
466 Protein structure determination using metagenome sequence data.
http://science.sciencemag.org/content/355/6322/294
465 Evolutionary drivers of thermoadaptation in enzyme catalysis.
http://science.sciencemag.org/content/355/6322/289?_ga=1.218330778.2031308027.1476376128
464 Targeted DNA sequencing and in situ mutation analysis using mobile phone microscopy.
http://www.nature.com/articles/ncomms13913
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