433 A small core protein of human adenoviruses is shown to associate with histones, sequestering proteins on host chromatin and preventing inflammatory proteins from being released and triggering inflammation.
http://www.nature.com/nature/journal/v535/n7610/full/nature18317.html
432 Visualization and analysis of gene expression in tissue sections by spatial transcriptomics.
http://science.sciencemag.org/content/353/6294/78
431 C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector.
http://science.sciencemag.org/content/early/2016/06/01/science.aaf5573
430 Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents.
http://www.pnas.org/content/113/19/5388.abstract
429 A prebiotically reasonable route to synthesize purine RNA bases A and G lends support to the RNA world hypothesis.
http://science.sciencemag.org/content/352/6287/833
428 Argonaute-associated short introns are a novel class of gene regulators.
http://www.nature.com/ncomms/2016/160513/ncomms11538/full/ncomms11538.html
427 RNA splicing is a primary link between genetic variation and disease.
http://science.sciencemag.org/content/352/6285/600
426 Mechanism of NMDA Receptor Inhibition and Activation.
http://www.cell.com/cell/fulltext/S0092-8674(16)30326-9
425 Structure of a bd oxidase indicates similar mechanisms for membrane-integrated oxygen reductases.
http://science.sciencemag.org/content/352/6285/583
424 The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA.
http://www.nature.com/nature/journal/v532/n7600/full/nature17945.html
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