244 Cytosolic DNA induces type I interferon via activation of STING; the immediate STING activator is produced by the recently identified DNA sensor cGAS and is shown here to be an unorthodox cyclic dinucleotide harbouring a 2′-5′ linkage between guanosine and adenosine.
http://www.nature.com/nature/journal/v498/n7454/full/nature12306.html
243 The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
http://www.nature.com/nature/journal/v498/n7454/full/nature12296.html
242 c-Myc modulates microRNA processing via the transcriptional regulation of Drosha.
http://www.nature.com/srep/2013/130605/srep01942/full/srep01942.html
241 The bromodomain protein Brd4 insulates chromatin from DNA damage signalling.
http://www.nature.com/nature/journal/v498/n7453/full/nature12147.html
240 Sodium/hydrogen exchanger NHA2 is critical for insulin secretion in β-cells.
http://www.pnas.org/content/110/24/10004.abstract
239 Analysis of SUMOylated proteins using SUMO-traps.
http://www.nature.com/srep/2013/130422/srep01690/full/srep01690.html
238 Sema3A, a member of the semaphorin family of proteins, is shown to regulate bone remodelling indirectly by modulating sensory nerve development in mice.
http://www.nature.com/nature/journal/v497/n7450/full/nature12115.html
237 Mitochondrial ribosomal proteins have been identified as longevity regulators in C. elegans and mammalian systems, their role in longevity is linked to mitonuclear protein imbalance and the mitochondrial unfolded protein response.
http://www.nature.com/nature/journal/v497/n7450/full/nature12188.html
236 Decreased activity of serine palmitoyl-CoA transferase is associated with asthma.
http://stm.sciencemag.org/content/5/186/186ra67.abstract
235 A protein implicated in oncogenesis is found to be critical for DNA replication in plants and animals.
http://www.sciencemag.org/content/340/6135/981.abstract
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