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Molecular Biology

Molecular Biology

Articles:

24  Cells respond to mechanical stress by rapid disassembly of caveolae. Sinha B. et al. (2011). Cell 144: 402-413.
http://www.cell.com/abstract/S0092-8674(10)01523-0

23  Mutant proteins as cancer-specific biomarkers. Wang Q, et al. (2011). PNAS 108:2444-2449.
http://www.pnas.org/content/108/6/2444.abstract

22  Multistage nanoparticle delivery system for deep penetration into tumor tissue. Wong C. et al. (2011). PNAS 108:2426-2431.
http://www.pnas.org/content/108/6/2426.abstract

21  miR-96 regulates the progression of differentiation in mammalian cochlear inner and outer hair cells. Kuhn S, et al. (2011). PNAS 108: 2355-2360.
http://www.pnas.org/content/108/6/2355.abstract

20  Transgenic birds expressing a short hairpin RNA that blocks viral polymerase hinder influenza transmission.
http://www.sciencemag.org/content/331/6014/223.abstract

19  The transition from androgen-dependent to castration-resistant prostate cancer is a lethal event. N-cadherin seems to be a major cause underlying this transition, and targeting this adhesion molecule may have positive clinical benefit. Tanaka H, et al. (2010). Nature Medicine 16:1414–1420.
http://www.nature.com/nm/journal/v16/n12/abs/nm.2236.html

18  Chemical synthesis of the mouse mitochondrial genome. Gibson DG et al. (2010). Nature Methods 7: 901-903.
http://www.nature.com/nmeth/journal/v7/n11/abs/nmeth.1515.html

17  A eukaryotic protein complex helps detect and destroy "aberrant" messenger RNAs stalled on ribosomes. Shoemaker CJ, et al. (2010) Science 330: 369-372.
http://www.sciencemag.org/cgi/content/abstract/330/6002/369

16  Structural mimics for L-cystine may provide drug treatments for certain types of kidney stones. Rimer JD, et al. (2010) Science 330: 337-341.
http://www.sciencemag.org/cgi/content/abstract/330/6002/337

15  Selective cell death mediated by small conditional RNAs. The authors describe small conditional RNAs that undergo hybridization chain reactions (HCR) to induce cell death via an innate immune response if and only if a cognate mRNA cancer marker is detected within a cell. Venkataraman S. et al. (2010). PNAS 107: 16777-16782.
http://www.pnas.org/content/107/39/16777.abstract

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