73 The release of tyramine during the flight response in nematodes activates the DAF-2/insulin–IGF pathway to downregulate cytoprotective mechanisms and shorten lifespan.
https://www.nature.com/articles/s41586-019-1524-5
72 A autonomous branch of the liver circadian clock is independent from all other clocks yet still dependent on the light-dark cycle.
https://www.cell.com/cell/fulltext/S0092-8674(19)30444-1
71 Extracellular tau is increased during wakefulness and with sleep deprivation, with potential relevance for Alzheimer’s disease.
http://science.sciencemag.org/content/363/6429/880
70 Sleep modulates haematopoiesis and protects against atherosclerosis.
https://www.nature.com/articles/s41586-019-0948-2
69 Chronic and acute stress monitoring by electrophysiological signals from adrenal gland.
https://www.pnas.org/content/116/4/1146
68 Constitutive Dicer1 phosphorylation accelerates metabolism and aging in vivo.
https://www.pnas.org/content/116/3/960
67 Giant tortoise genomes provide insights into longevity and age-related disease.
https://www.nature.com/articles/s41559-018-0733-x
66 Leak potassium channels regulate sleep duration.
http://www.pnas.org/content/115/40/E9459
65 A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine.
http://stm.sciencemag.org/content/10/458/eaat8806
64 Human-like Cmah inactivation in mice increases running endurance and decreases muscle fatigability: implications for human evolution.
http://rspb.royalsocietypublishing.org/content/285/1886/20181656
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