493 An RNA-targeting Cas9 system induces degradation of microsatellite repeat expansion RNAs, highlighting the potential of RNA-targeting CRISPR systems for therapeutic purposes.
http://www.cell.com/cell/fulltext/S0092-8674(17)30817-6
492 Type III CRISPR–Cas systems produce cyclic oligoadenylate second messengers.
https://www.nature.com/nature/journal/v548/n7669/full/nature23467.html
491 The cytoplasmic DNA sensor cGAS detects DNA in ruptured micronuclei and activates an innate immune response.
http://www.nature.com/nature/journal/v548/n7668/full/nature23449.html
490 A cyclic oligonucleotide signaling pathway in type III CRISPR-Cas systems.
http://science.sciencemag.org/content/357/6351/605
489 Disabling Cas9 by an anti-CRISPR DNA mimic.
http://advances.sciencemag.org/content/3/7/e1701620
488 RNase III from all three domains of life elicits RNA-targeting antiviral activity that is independent of, and possibly predates, other known eukaryotic antiviral systems.
http://www.nature.com/nature/journal/v547/n7661/full/nature22990.html
487 Restoring auditory cortex plasticity in adult mice by restricting thalamic adenosine signaling.
http://science.sciencemag.org/content/356/6345/1352
486 Structural Basis of Egg Coat-Sperm Recognition at Fertilization.
http://www.cell.com/cell/fulltext/S0092-8674(17)30594-9
485 Structural basis of CRISPR–SpyCas9 inhibition by an anti-CRISPR protein.
https://www.nature.com/nature/journal/v546/n7658/full/nature22377.html
484 An Atomic Structure of the Human Spliceosome.
http://www.cell.com/cell/fulltext/S0092-8674(17)30487-7
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