503 DNA synthesis from diphosphate substrates by DNA polymerases.
http://www.pnas.org/content/115/5/980
502 Dicer uses distinct modules for recognizing dsRNA termini.
http://science.sciencemag.org/content/359/6373/329
501 The retrotransposition of L1 is controlled by functionally diverse genes at the transcriptional or post-transcriptional levels, and its silencing can lead to the downregulation of host gene expression.
https://www.nature.com/articles/nature25179
500 Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents.
https://www.nature.com/articles/nature25164
499 An RNA-editing technology is developed to efficiently and specifically deplete and correct RNA directly in mammalian cells.
http://science.sciencemag.org/content/358/6366/1019
498 Charged residues in the H-NS linker drive DNA binding and gene silencing in single cells.
http://www.pnas.org/content/114/47/12560.abstract
497 Generation of specific inhibitors of SUMO-1– and SUMO-2/3–mediated protein-protein interactions using Affimer (Adhiron) technology.
http://stke.sciencemag.org/content/10/505/eaaj2005
496 Origin of the RNA world: The fate of nucleobases in warm little ponds.
http://www.pnas.org/content/114/43/11327
495 Switch to Standard View Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes.
http://www.cell.com/cell/fulltext/S0092-8674(17)31057-7
494 The transcription fidelity factor GreA impedes DNA break repair.
https://www.nature.com/nature/journal/v550/n7675/full/nature23907.html
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