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Cancer Biology

Cancer Biology

 
1337 Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer
https://www.science.org/doi/10.1126/science.adh4567

1336 A TME-enlightened protein-binding photodynamic nanoinhibitor for highly effective oncology treatment
https://www.pnas.org/doi/10.1073/pnas.2321545121

1335 OTUB2 silencing promotes ovarian cancer via mitochondrial metabolic reprogramming and can be synthetically targeted by CA9 inhibition
https://www.pnas.org/doi/10.1073/pnas.2315348121

1334 Decorin suppresses tumor lymphangiogenesis: A mechanism to curtail cancer progression
https://www.pnas.org/doi/10.1073/pnas.2317760121

1333 Liver cancer development driven by the AP-1/c-Jun~Fra-2 dimer through c-Myc
https://www.pnas.org/doi/10.1073/pnas.2404188121

1332 A blueprint for tumor-infiltrating B cells across human cancers
https://www.science.org/doi/10.1126/science.adj4857

1331 Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment
https://www.pnas.org/doi/10.1073/pnas.2309957121

1330 Mycoplasma DnaK expression increases cancer development in vivo upon DNA damage
https://www.pnas.org/doi/10.1073/pnas.2320859121

1329 Femtosecond pulsed laser photodynamic therapy activates melanin and eradicates malignant melanoma
https://www.pnas.org/doi/10.1073/pnas.2316303121

1328 SOX17 enables immune evasion of early colorectal adenomas and cancers
https://www.nature.com/articles/s41586-024-07135-3

1327 Cancer-on-a-chip model shows that the adenomatous polyposis coli mutation impairs T cell engagement and killing of cancer spheroids
https://www.pnas.org/doi/10.1073/pnas.2316500121

1326 An immunogenetic basis for lung cancer risk
https://www.science.org/doi/10.1126/science.adi3808

1325 Siglec-15/sialic acid axis as a central glyco-immune checkpoint in breast cancer bone metastasis
https://www.pnas.org/doi/10.1073/pnas.2312929121

1324 Inhaled mRNA nanoparticles dual-targeting cancer cells and macrophages in the lung for effective transfection
https://www.pnas.org/doi/10.1073/pnas.2304966120

1323 Viral nanoparticle vaccines against S100A9 reduce lung tumor seeding and metastasis
https://www.pnas.org/doi/10.1073/pnas.2221859120

1322 Crosstalk between small-cell lung cancer cells and astrocytes mimics brain development to promote brain metastasis
https://www.nature.com/articles/s41556-023-01241-6

1321 Probiotic-guided CAR-T cells for solid tumor targeting
https://www.science.org/doi/10.1126/science.add7034

1320 A vertebral skeletal stem cell lineage driving metastasis.
https://www.nature.com/articles/s41586-023-06519-1

1319 Epitope engineering of donor haematopoietic stem/progenitor cells endows haematopoietic lineages with selective resistance to CAR T cells or monoclonal antibodies, without affecting protein function or regulation, enabling the targeting of genes that are essential for leukaemia survival and reducing the risk of tumour immune escape.
https://www.nature.com/articles/s41586-023-06496-5

1318 Rationally designed chimeric PI3K-BET bromodomain inhibitors elicit curative responses in MYC-driven lymphoma.
https://www.pnas.org/doi/10.1073/pnas.2306414120

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