Cancer Biology

975 Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models.

974 DNA adducts in cells and animals exposed to colibactin-producing gut microbes shed light on the mode of action of a cancer-linked genotoxin.

973 Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells.

972 Commensal Microbiota Promote Lung Cancer Development via γδ T Cells.

971 Inhibition of histone methyltransferase DOT1L silences ERα gene and blocks proliferation of antiestrogen-resistant breast cancer cells.

970 Losartan treatment enhances chemotherapy efficacy and reduces ascites in ovarian cancer models by normalizing the tumor stroma.

969 Identification and sequencing of circulating tumour DNA in the cerebrospinal fluid of patients with glioma.

968 A consortium of 11 bacterial strains from the healthy human gut microbiota can strongly induce interferon-γ-producing CD8 T cells in the intestine, and enhance both resistance to bacterial infection and the therapeutic efficacy of immune checkpoint inhibitors.

967 Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth.

966 Therapeutic targeting of the RB1 pathway in retinoblastoma with the oncolytic adenovirus VCN-01.

965 Deep learning using tumor HLA peptide mass spectrometry datasets improves neoantigen identification

964 An oncolytic herpesvirus expressing E-cadherin improves survival in mouse models of glioblastoma.

963 Central body fatness is a stronger predictor of cancer risk than overall body size.

962 Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti–PD-1 for tumor abrogation.

961 Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody.

960 IL-15 is a component of the inflammatory milieu in the tumor microenvironment promoting antitumor responses.

959 Tissue-resident memory CD8+ T cells promote melanoma–immune equilibrium in skin.

958 A large network of bacterial proteins promotes endogenous DNA damage and mutations when upregulated, acting like protein carcinogens, and has human homologs that form a cancer predictive network.

957 Actively personalized vaccination trial for newly diagnosed glioblastoma.

956 Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.

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