Cancer Biology

 
1141 The dopamine receptor antagonist trifluoperazine prevents phenotype conversion and improves survival in mouse models of glioblastoma.
https://www.pnas.org/content/117/20/11085

1140 Natural hybridization reveals incompatible alleles that cause melanoma in swordtail fish.
https://science.sciencemag.org/content/368/6492/731

1139 Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I.
https://www.nature.com/articles/s41586-020-2229-5

1138 Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer.
https://www.cell.com/cell/fulltext/S0092-8674(20)30270-1

1137 Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer.
https://www.cell.com/cell/fulltext/S0092-8674(20)30341-X

1136 The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution.
https://www.cell.com/cell/fulltext/S0092-8674(20)30346-9

1135 Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.
https://science.sciencemag.org/content/368/6489/387

1134 Germline mutations in the Elongator complex gene ELP1 predispose individuals to the development of childhood medulloblastoma.
https://www.nature.com/articles/s41586-020-2164-5

1133 Integrating genomic features for non-invasive early lung cancer detection.
https://www.nature.com/articles/s41586-020-2140-0

1132 IL-6 blockade reverses bone marrow failure induced by human acute myeloid leukemia.
https://stm.sciencemag.org/content/12/538/eaax5104

1131 Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling.
https://stm.sciencemag.org/content/12/537/eaaw0262

1130 Control of brain tumor growth by reactivating myeloid cells with niacin.
https://stm.sciencemag.org/content/12/537/eaay9924

1129 Cysteine depletion induces pancreatic tumor ferroptosis in mice.
https://science.sciencemag.org/content/368/6486/85

1128 Microbiome analyses of blood and tissues suggest cancer diagnostic approach.
https://www.nature.com/articles/s41586-020-2095-1

1127 Inhibiting a specific isoform of TGFβ augments the effectiveness of checkpoint blockade therapy in cancer treatment.
https://stm.sciencemag.org/content/12/536/eaay8456

1126 Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis.
https://science.sciencemag.org/content/367/6485/1468

1125 SOX4-mediated repression of specific tRNAs inhibits proliferation of human glioblastoma cells.
https://www.pnas.org/content/117/11/5782

1124 Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8+ T cell stemness and antitumor immunity.
https://www.pnas.org/content/117/11/6047

1123 Peripheral T cell expansion predicts tumour infiltration and clinical response.
https://www.nature.com/articles/s41586-020-2056-8

1122 Epigenetic therapy inhibits metastases by disrupting premetastatic niches.
https://www.nature.com/articles/s41586-020-2054-x

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