Cancer Biology

 
861 Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.
http://science.sciencemag.org/content/359/6378/920

860 Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence.
http://www.pnas.org/content/115/8/1801

859 Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy.
http://stm.sciencemag.org/content/10/428/eaaf7444

858 Renal cell cancers with mutations in a specific chromatin regulator have a better clinical response to immunotherapy.
http://science.sciencemag.org/content/359/6377/801

857 Inactivation of a chromatin remodeling complex in tumor cells enhances their sensitivity to killing by T cells.
http://science.sciencemag.org/content/359/6377/770

856 Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury.
https://www.nature.com/articles/nm.4470

855 Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.
https://www.nature.com/articles/nm.4464

854 A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.
https://www.nature.com/articles/nm.4474

853 Targeting IRF3 as a YAP agonist therapy against gastric cancer.
http://jem.rupress.org/content/215/2/699

852 Asparagine bioavailability governs metastasis in a model of breast cancer.
https://www.nature.com/articles/nature25465

851 Targeting of p53- and PUMA-dependent apoptosis protects intestinal stem cells, but not cancer cells, against chemotherapy.
http://stm.sciencemag.org/content/10/427/eaam7610

850 HER kinase inhibition in patients with HER2- and HER3-mutant cancers.
https://www.nature.com/articles/nature25475

849 Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria.
http://science.sciencemag.org/content/359/6375/592

848 Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy.
http://science.sciencemag.org/content/359/6375/582

847 Eradication of spontaneous malignancy by local immunotherapy.
http://stm.sciencemag.org/content/10/426/eaan4488

846 Elevated d-2-hydroxyglutarate during colitis drives progression to colorectal cancer.
http://www.pnas.org/content/115/5/1057

845 Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells.
https://www.nature.com/articles/s41467-018-02865-1

844 Detection and localization of surgically resectable cancers with a multi-analyte blood test.
http://science.sciencemag.org/content/early/2018/01/17/science.aar3247

843 Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett’s esophagus.
http://stm.sciencemag.org/content/10/424/eaao5848

842 Rapid drug screen using 3D tumor organoids.
http://stm.sciencemag.org/content/10/423/eaar7507

Free Images for Presentation: sunipix SUNIPIX