804 Tumor-associated B-cells induce tumor heterogeneity and therapy resistance.
https://www.nature.com/articles/s41467-017-00452-4
803 Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanoma.
http://stm.sciencemag.org/content/9/407/eaal4712
802 Using unique barcodes for tumour cells, the authors explore the dynamics of human glioblastoma subpopulations, and suggest that clonal heterogeneity emerges through stochastic fate decisions of a neutral proliferative hierarchy.
http://www.nature.com/nature/journal/v549/n7671/full/nature23666.html
801 Large-scale enhancer reprogramming directed by transcription factors such as FOXA1 drives metastasis in the organoid model of pancreatic cancer.
http://www.cell.com/cell/fulltext/S0092-8674(17)30814-0
800 Distinct tumor immune microenvironments co-exist within a single individual and may help to explain the heterogeneous fates of metastatic lesions often observed post-therapy.
http://www.cell.com/cell/fulltext/S0092-8674(17)30832-2
799 Molecular machines open cell membranes.
http://www.nature.com/nature/journal/v548/n7669/full/nature23657.html?foxtrotcallback=true
798 Identification of essential genes for cancer immunotherapy.
https://www.nature.com/nature/journal/v548/n7669/full/nature23477.html
797 CDK4/6 inhibition triggers anti-tumour immunity.
http://www.nature.com/nature/journal/v548/n7668/full/nature23465.html
796 SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis.
https://www.nature.com/articles/s41467-017-00396-9
795 Ultrastable Near-Infrared Conjugated-Polymer Nanoparticles for Dually Photoactive Tumor Inhibition.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201700487/full
794 Sequentially Responsive Shell-Stacked Nanoparticles for Deep Penetration into Solid Tumors.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201701170/full
793 Synergistic Immuno Photothermal Nanotherapy (SYMPHONY) for the Treatment of Unresectable and Metastatic Cancers.
http://www.nature.com/articles/s41598-017-09116-1
792 A pathology atlas of the human cancer transcriptome.
http://science.sciencemag.org/content/357/6352/eaan2507
791 An approach to suppress the evolution of resistance in BRAFV600E-mutant cancer.
http://www.nature.com/nm/journal/v23/n8/abs/nm.4369.html
790 FolamiRs: Ligand-targeted, vehicle-free delivery of microRNAs for the treatment of cancer.
http://stm.sciencemag.org/content/9/401/eaam9327
789 A pan-cancer biomarker is identified that can predict successful response to cancer immunotherapy in human patients.
http://science.sciencemag.org/content/357/6349/409
788 In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target.
http://www.nature.com/nature/journal/v547/n7664/full/nature23270.html
787 Genome editing abrogates angiogenesis in vivo.
https://www.nature.com/articles/s41467-017-00140-3
786 A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma.
http://stm.sciencemag.org/content/9/399/eaaa0984
785 Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer.
http://www.nature.com/nature/journal/v547/n7662/full/nature23003.html
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