Proteome

Articles:
21  Human-like Cmah inactivation in mice increases running endurance and decreases muscle fatigability: implications for human evolution.
http://rspb.royalsocietypublishing.org/content/285/1886/20181656

20  Cell-Penetrating Peptide Mediates Intracellular Membrane Passage of Human Papillomavirus L2 Protein to Trigger Retrograde Trafficking.
https://www.cell.com/cell/fulltext/S0092-8674(18)30958-9

19  SIRT6 deficiency results in developmental retardation in cynomolgus monkeys.
https://www.nature.com/articles/s41586-018-0437-z

18  A deep proteome analysis of human serum reveals the relationship between disease and genetics.
http://science.sciencemag.org/content/361/6404/769

17  A distinct abundant group of microbial rhodopsins discovered using functional metagenomics.
https://www.nature.com/articles/s41586-018-0225-9?utm_source=Nature_community&utm_medium=Community_sites&utm_content=BenJoh-Nature-MultipleJournals-Mi

16  Efficient encapsulation of proteins with random copolymers.
http://www.pnas.org/content/115/26/6578

15  Loss of esophageal SPINK7 unleashes protease activity, impairs barrier function, and induces proinflammatory responses.
http://stm.sciencemag.org/content/10/444/eaap9736

14  A knock-in mutation in beclin 1 that increases autophagy in mice extends animal lifespan, improves healthspan, and also rescues early lethality in mice deficient in the anti-ageing protein klotho.
https://www.nature.com/articles/s41586-018-0162-7

13  Xenoprotein engineering via synthetic libraries.
http://www.pnas.org/content/115/23/E5298

12  Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes.
https://www.nature.com/articles/s41586-018-0153-8

11  The histone demethylase KDM6B regulates temperature-dependent sex determination in a turtle species.
http://science.sciencemag.org/content/360/6389/645

10  A system that combines nanoscale synthesis and affinity ranking enables high-throughput screening of reaction conditions and bioactivity for a given protein target, accelerating the process of drug discovery.
https://www.nature.com/articles/s41586-018-0056-8

9  Mosquito-Derived Anophelin Sulfoproteins Are Potent Antithrombotics.
https://pubs.acs.org/doi/10.1021/acscentsci.7b00612

8  A bound reaction intermediate sheds light on the mechanism of nitrogenase.
http://science.sciencemag.org/content/359/6383/1484

7  Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule.
http://science.sciencemag.org/content/359/6383/eaaq0939

6  Light-activated protein interaction with high spatial subcellular confinement.
http://www.pnas.org/content/115/10/E2238

5  Optically functional isoxanthopterin crystals in the mirrored eyes of decapod crustaceans.
http://www.pnas.org/content/115/10/2299

4  The mechanism by which mitochondrial outer membrane proteins are inserted is elucidated.
http://science.sciencemag.org/content/359/6373/eaah6834

3  Phase separation of a yeast prion protein promotes cellular fitness.
http://science.sciencemag.org/content/359/6371/eaao5654

2  A Method for the Acute and Rapid Degradation of Endogenous Proteins.
http://www.cell.com/cell/fulltext/S0092-8674(17)31255-2

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