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Structural Biology

Structural Biology

167 De novo design of luciferases using deep learning.

166 Structure-based design of bitopic ligands for the µ-opioid receptor.

165 Structures of the entire human opioid receptor family.

164 Mapping the Accessory Proteins (Orfs) of Severe Acute Respiratory Syndrome Coronavirus 2.

163 Geometric deep learning of RNA structure.

162 Computational design of a synthetic PD-1 agonist.

161 Structural basis of omega-3 fatty acid transport across the blood–brain barrier.

160 A structure of RNA polymerase II in complex with spliceosomal particle U1 snRNP reveals how transcription and RNA splicing are coupled.

159 Structures of the iron transporter ferroportin and the peptide hormone hepcidin suggest how iron homeostasis is tightly regulated.

158 Computational design of transmembrane pores.

157 Structures of human pannexin 1 reveal ion pathways and mechanism of gating.

156 A mass spectrometry analysis reveals the glycan composition at all glycosylation sites on the SARS-CoV-2 spike protein.

155 Structure of the RNA-dependent RNA polymerase from COVID-19 virus.

154 The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage.

153 The Structure of the Membrane Protein of SARS-CoV-2 Resembles the Sugar Transporter semiSWEET.

152 Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors.

151 Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry.

150 Structural insight into arenavirus replication machinery.

149 Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures.

148 Cryo-EM Structure of the Human Cannabinoid Receptor CB2-Gi Signaling Complex.

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