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48 The live biotherapeutic SYNB1353 decreases plasma methionine via directed degradation in animal models and healthy volunteers

47 Hydroxyurea Dose Escalation for Sickle Cell Anemia in Sub-Saharan Africa.

46 Phototherapy and extracorporeal membrane oxygenation facilitate removal of carbon monoxide in rats.

45 A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease.

44 Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria.

43 RSK2 contributes to myogenic vasoconstriction of resistance arteries by activating smooth muscle myosin and the Na+/H+ exchanger.

42 Semisynthetic sensor proteins enable metabolic assays at the point of care.

41 In pilot studies of pregnant women, RNA-based tests of maternal blood predicted delivery date and risk of early childbirth.

40 Vasopressin stimulates the proliferation and differentiation of red blood cell precursors and improves recovery from anemia.

39 Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals.

38 Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia.

37 Interleukin-12 and Interleukin-23 Blockade in Leukocyte Adhesion Deficiency Type 1.

36 Quarter-dose quadruple combination therapy for initial treatment of hypertension.

35 Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease.

34 Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors.

33 Blockade of protease-activated receptor-4 (PAR4) provides robust antithrombotic activity with low bleeding.

32 Five-coordinate H64Q neuroglobin as a ligand-trap antidote for carbon monoxide poisoning.

31 An injectable shear-thinning biomaterial for endovascular embolization.

30 An injectable shear-thinning biomaterial for endovascular embolization.

29 Cord-Blood Transplantation in Patients with Minimal Residual Disease.

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