532 LZTR1 is a regulator of RAS ubiquitination and signaling.
http://science.sciencemag.org/content/362/6419/1171
531 A DNA methylation reader complex that enhances gene transcription.
http://science.sciencemag.org/content/362/6419/1182
530 CDK12 regulates DNA repair genes by suppressing intronic polyadenylation.
https://www.nature.com/articles/s41586-018-0758-y
529 Physical positioning markedly enhances brain transduction after intrathecal AAV9 infusion.
http://advances.sciencemag.org/content/4/11/eaau9859
528 The authors use a machine-learning algorithm to predict the spectrum of CRISPR–Cas9-nuclease-mediated DNA repair outcomes at human genomic target sites.
https://www.nature.com/articles/s41586-018-0686-x
527 Chromatin modifiers Mdm2 and RNF2 prevent RNA:DNA hybrids that impair DNA replication.
http://www.pnas.org/content/115/48/E11311
526 Programmed DNA destruction by miniature CRISPR-Cas14 enzymes.
http://science.sciencemag.org/content/362/6416/839
525 SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism.
http://science.sciencemag.org/content/362/6416/eaat9528
524 Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH.
http://stke.sciencemag.org/content/11/555/eaau7987
523 Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.
https://www.nature.com/articles/s41586-018-0629-6
|
