Molecular Biology

Articles:

498  Charged residues in the H-NS linker drive DNA binding and gene silencing in single cells.
http://www.pnas.org/content/114/47/12560.abstract

497  Generation of specific inhibitors of SUMO-1– and SUMO-2/3–mediated protein-protein interactions using Affimer (Adhiron) technology.
http://stke.sciencemag.org/content/10/505/eaaj2005

496  Origin of the RNA world: The fate of nucleobases in warm little ponds.
http://www.pnas.org/content/114/43/11327

495  Switch to Standard View Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes.
http://www.cell.com/cell/fulltext/S0092-8674(17)31057-7

494  The transcription fidelity factor GreA impedes DNA break repair.
https://www.nature.com/nature/journal/v550/n7675/full/nature23907.html

493  An RNA-targeting Cas9 system induces degradation of microsatellite repeat expansion RNAs, highlighting the potential of RNA-targeting CRISPR systems for therapeutic purposes.
http://www.cell.com/cell/fulltext/S0092-8674(17)30817-6

492  Type III CRISPR–Cas systems produce cyclic oligoadenylate second messengers.
https://www.nature.com/nature/journal/v548/n7669/full/nature23467.html

491  The cytoplasmic DNA sensor cGAS detects DNA in ruptured micronuclei and activates an innate immune response.
http://www.nature.com/nature/journal/v548/n7668/full/nature23449.html

490  A cyclic oligonucleotide signaling pathway in type III CRISPR-Cas systems.
http://science.sciencemag.org/content/357/6351/605

489  Disabling Cas9 by an anti-CRISPR DNA mimic.
http://advances.sciencemag.org/content/3/7/e1701620

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