101 Dim light in the evening causes coordinated realignment of circadian rhythms, sleep, and short-term memory.

100 Neuro-mesenchymal units control ILC2 and obesity via a brain–adipose circuit.

99 Chronic social isolation signals starvation and reduces sleep in Drosophila.

98 Clock proteins and training modify exercise capacity in a daytime-dependent manner.

97 Genetic insights into biological mechanisms governing human ovarian ageing.

96 Daily energy expenditure through the human life course.

95 Sleep loss drives acetylcholine- and somatostatin interneuron–mediated gating of hippocampal activity to inhibit memory consolidation.

94 Microbiota from young mice counteracts selective age-associated behavioral deficits.

93 An aged immune system drives senescence and ageing of solid organs.

92 In aged mice, inhibition of prostaglandin E2 (PGE2) signalling through its receptor EP2 improves cellular bioenergetics, reduces inflammatory responses and restores hippocampal plasticity to youthful levels, resulting in an improvement in spatial memory and cognition.

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