99 Chronic social isolation signals starvation and reduces sleep in Drosophila.
https://www.nature.com/articles/s41586-021-03837-0
98 Clock proteins and training modify exercise capacity in a daytime-dependent manner.
https://www.pnas.org/content/118/35/e2101115118
97 Genetic insights into biological mechanisms governing human ovarian ageing.
https://www.nature.com/articles/s41586-021-03779-7
96 Daily energy expenditure through the human life course.
https://science.sciencemag.org/content/373/6556/808
95 Sleep loss drives acetylcholine- and somatostatin interneuron–mediated gating of hippocampal activity to inhibit memory consolidation.
https://www.pnas.org/content/118/32/e2019318118
94 Microbiota from young mice counteracts selective age-associated behavioral deficits.
https://www.nature.com/articles/s43587-021-00093-9
93 An aged immune system drives senescence and ageing of solid organs.
https://www.nature.com/articles/s41586-021-03547-7
92 In aged mice, inhibition of prostaglandin E2 (PGE2) signalling through its receptor EP2 improves cellular bioenergetics, reduces inflammatory responses and restores hippocampal plasticity to youthful levels, resulting in an improvement in spatial memory and cognition.
https://www.nature.com/articles/s41586-020-03160-0
91 Increased activity of prostaglandin E2 in older mice helps restore lost muscle.
https://science.sciencemag.org/content/371/6528/eabc8059
90 Inactivation of the histone acetyltransferase gene KAT7 prolongs survival in naturally aged mice and progeroid mice that age prematurely.
https://stm.sciencemag.org/content/13/575/eabd2655
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