58 Artemisinins ameliorate polycystic ovarian syndrome by mediating LONP1-CYP11A1 interaction
https://www.science.org/doi/10.1126/science.adk5382
57 Chronotherapy with a glucokinase activator profoundly improves metabolism in obese Zucker rats.
https://www.science.org/doi/10.1126/scitranslmed.abh1316
56 Dorzagliatin in drug-naïve patients with type 2 diabetes: a randomized, double-blind, placebo-controlled phase 3 trial.
https://www.nature.com/articles/s41591-022-01802-6
55 Dynamin deficiency causes insulin secretion failure and hyperglycemia.
https://www.pnas.org/content/118/32/e2021764118
54 Lactation improves pancreatic β cell mass and function through serotonin production.
https://stm.sciencemag.org/content/12/541/eaay0455
53 In mouse studies, metformin treatment results in increased secretion of growth/differentiation factor 15 (GDF15), which prevents weight gain in response to high-fat diet, and GDF15-independent lowering of circulating blood glucose.
https://www.nature.com/articles/s41586-019-1911-y
52 Habenular TCF7L2 links nicotine addiction to diabetes.
https://www.nature.com/articles/s41586-019-1653-x
51 Treatment of type 2 diabetes with the designer cytokine IC7Fc.
https://www.nature.com/articles/s41586-019-1601-9
50 Intensive Glucose Control in Patients with Type 2 Diabetes — 15-Year Follow-up.
https://www.nejm.org/doi/full/10.1056/NEJMoa1806802
49 Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy.
https://www.nejm.org/doi/full/10.1056/NEJMoa1811744
48 Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes.
https://www.nejm.org/doi/full/10.1056/NEJMoa1812389
47 Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
https://www.nejm.org/doi/full/10.1056/NEJMoa1804988?query=featured_home
46 Estrogens Promote Misfolded Proinsulin Degradation to Protect Insulin Production and Delay Diabetes.
https://www.cell.com/cell-reports/fulltext/S2211-1247(18)30914-8
45 Ionic liquids for oral insulin delivery.
http://www.pnas.org/content/115/28/7296
44 Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes.
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(18)30253-5
43 Smartphone-controlled optogenetically engineered cells enable semiautomatic glucose homeostasis in diabetic mice.
http://stm.sciencemag.org/content/9/387/eaal2298
42 3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)30069-7/fulltext
41 Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 5-Year Outcomes.
http://www.nejm.org/doi/full/10.1056/NEJMoa1600869
40 Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease.
http://stm.sciencemag.org/content/9/377/eaai8700
39 The authors inject mouse pluripotent stem cells into pancreatogenesis-disabled rat blastocysts and thereby generate rats with mouse pancreata from which the islets, when transplanted into mice, can provide a long-term cure for symptoms of diabetes, without continuous immunosuppression.
http://www.nature.com/nature/journal/v542/n7640/full/nature21070.html
38 Metformin Is Associated With Higher Relative Abundance of Mucin-Degrading Akkermansia muciniphila and Several Short-Chain Fatty Acid-Producing Microbiota in the Gut.
http://care.diabetesjournals.org/content/40/1/54.long
37 Closed-loop insulin delivery in inpatients with type 2 diabetes: a randomised, parallel-group trial.
http://www.thelancet.com/journals/landia/article/PIIS2213-8587(16)30280-7/fulltext
36 Outpatient Glycemic Control with a Bionic Pancreas in Type 1 Diabetes.
http://www.nejm.org/doi/full/10.1056/NEJMoa1314474
35 Novel glucose-sensing technology and hypoglycaemia in type 1 diabetes.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)31535-5/fulltext
34 Home Use of an Artificial Beta Cell in Type 1 Diabetes.
http://www.nejm.org/doi/full/10.1056/NEJMoa1509351
33 Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients.
http://www.pnas.org/content/112/7/2139.abstract
32 Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis.
http://www.nature.com/nm/journal/v20/n7/abs/nm.3579.html
31 Outpatient Glycemic Control with a Bionic Pancreas in Type 1 Diabetes.
http://www.nejm.org/doi/full/10.1056/NEJMoa1314474
30 Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis.
http://www.nature.com/nm/journal/v20/n6/abs/nm.3549.html
29 Null Mutation in Hormone-Sensitive Lipase Gene and Risk of Type 2 Diabetes.
http://www.nejm.org/doi/full/10.1056/NEJMoa1315496
28 Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 3-Year Outcomes.
http://www.nejm.org/doi/full/10.1056/NEJMoa1401329
27 Immunosuppression in acutely decompensated cirrhosis is mediated by prostaglandin E2.
http://www.nature.com/nm/journal/v20/n5/abs/nm.3516.html
26 Constitutive Activation of PKA Catalytic Subunit in Adrenal Cushing's Syndrome.
http://www.nejm.org/doi/full/10.1056/NEJMoa1310359
25 Growth hormone prevents the development of autoimmune diabetes.
http://www.pnas.org/content/110/48/E4619.abstract
24 Efficacy and safety of recombinant human parathyroid hormone (1—84) in hypoparathyroidism (REPLACE).
http://www.thelancet.com/journals/landia/article/PIIS2213-8587(13)70106-2/abstract
23 Low-dose interleukin 2 in patients with type 1 diabetes.
http://www.thelancet.com/journals/landia/article/PIIS2213-8587(13)70113-X/abstract
22 Combined Angiotensin Inhibition for the Treatment of Diabetic Nephropathy.
http://www.nejm.org/doi/full/10.1056/NEJMoa1303154
21 Transplantation of human islets without immunosuppression.
http://www.pnas.org/content/110/47/19054.abstract
20 Restoration of the Unfolded Protein Response in Pancreatic β Cells Protects Mice Against Type 1 Diabetes.
http://stm.sciencemag.org/content/5/211/211ra156.abstract
19 Glucagon-like peptide-1 receptor imaging for the localisation of insulinomas: a prospective multicentre imaging study.
http://www.thelancet.com/journals/landia/article/PIIS2213-8587(13)70049-4/fulltext
18 Reprogramming of Intestinal Glucose Metabolism and Glycemic Control in Rats After Gastric Bypass.
http://www.sciencemag.org/content/341/6144/406.abstract
17 Plasmid-Encoded Proinsulin Preserves C-Peptide While Specifically Reducing Proinsulin-Specific CD8+ T Cells in Type 1 Diabetes.
http://stm.sciencemag.org/content/5/191/191ra82
16 Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation.
http://www.cell.com/abstract/S0092-8674(13)00449-2
15 Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes.
http://jem.rupress.org/content/210/1/191.abstract
14 Rats given alcohol to simulate binge drinking exhibit the first signs of diabetes, a result of altered insulin action in the brain.
http://stm.sciencemag.org/content/5/170/170ra14.abstract
13 Treating Diabetes and Obesity with an FGF21-Mimetic Antibody Activating the βKlotho/FGFR1c Receptor Complex.
http://stm.sciencemag.org/content/4/162/162ra153.abstract
12 Sleep deficiency and out-of-synch circadian rhythms impair pancreatic insulin secretion, a possible precursor to metabolic syndrome and diabetes.
http://stm.sciencemag.org/content/4/129/129ra43.abstract
11 MicroRNA 135 Regulates HOXA10 Expression in Endometriosis.
http://jcem.endojournals.org/content/96/12/E1925.abstract
10 Urine Steroid Metabolomics as a Biomarker Tool for Detecting Malignancy in Adrenal Tumors.
http://jcem.endojournals.org/content/96/12/3775.abstract
9 MicroRNAs in Thyroid Cancer.
http://jcem.endojournals.org/content/96/11/3326.abstract
8 Angiotensin II Signaling Promotes Follicle Growth and Dominance in Cattle.
http://endo.endojournals.org/content/152/12/4957.abstract
7 Analysis of Fertility-Related Soluble Mediators in Human Uterine Fluid Identifies VEGF as a Key Regulator of Embryo Implantation.
http://endo.endojournals.org/content/152/12/4948.abstract
6 Aldosterone-Producing Adenoma Formation in the Adrenal Cortex Involves Expression of Stem/Progenitor Cell Markers.
http://endo.endojournals.org/content/152/12/4753.abstract
5 Depletion of Bhmt Elevates sonic hedgehog Transcript Level and Increases β-Cell Number in Zebrafish.
http://endo.endojournals.org/content/152/12/4706.abstract
4 Calcium Insufficiency Accelerates Type 1 Diabetes in Vitamin D Receptor-Deficient Nonobese Diabetic (NOD) Mice.
http://endo.endojournals.org/content/152/12/4620.abstract
3 Cadherin Engagement Protects Human β-Cells from Apoptosis.
http://endo.endojournals.org/content/152/12/4601.abstract
2 Sirt1 Is a Regulator of Bone Mass and a Repressor of Sost Encoding for Sclerostin, a Bone Formation Inhibitor.
http://endo.endojournals.org/content/152/12/4514.abstract
1 Dietary Phosphate Restriction Normalizes Biochemical and Skeletal Abnormalities in a Murine Model of Tumoral Calcinosis.
http://endo.endojournals.org/content/152/12/4504.abstract
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